Tetrahydrofuran → Methyl 4-(3-carbamoyl-6-chloropyridin-2-ylamino)benzoate
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:23][Si:24]([N-:25][Si:26]([CH3:27])([CH3:28])[CH3:29])([CH3:30])[CH3:31].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH2:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1.[Li+:32].[NH2:12][c:13]1[cH:14][cH:15][c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22]1>>[c:2]1([NH:12][c:13]2[cH:14][cH:15][c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22]2)[c:3]([C:4](=[O:5])[NH2:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1Participants
6
Sources & evidence
- ORD record
- ord-55437941716e43a19d7d91a2f3828c51
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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