Dimethylformamide → ethyl 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)-2-methylpropanoate

HRID 134577Notes

Reaction equation

HRID 134577 reaction equation
[Br:1][c:2]1[n:3](-[c:8]2[cH:9][cH:10][c:11]([CH:18]3[CH2:19][CH2:20]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[c:4]([SH:7])[n:5][n:6]1.[Br:21][C:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])([CH3:28])[CH3:29].[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[Br:1][c:2]1[n:3](-[c:8]2[cH:9][cH:10][c:11]([CH:18]3[CH2:19][CH2:20]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[c:4]([S:7][C:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])([CH3:28])[CH3:29])[n:5][n:6]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 81531DiisopropylethylamineHCID 178527930HCID 178527930, compound

Product 1

HCID 57811357ethyl 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)-2-methylpropanoate

Sources & evidence

ORD record
ord-c24363b37bcf4a26b8d6552ec98da7d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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