Piperidine → HCID 73446797, compound

HRID 1348524Notes

Reaction equation

[CH:1]([C:4]1[O:5][C:6]([CH3:15])=[CH:7][C:8](=[C:10]([C:13]#[N:14])[C:11]#[N:12])[CH:9]=1)([CH3:3])[CH3:2].[C:16]1([C:22]2[CH2:26][CH:25]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[N:24]([C:33]3[CH:40]=[CH:39][C:36]([CH:37]=O)=[CH:35][CH:34]=3)[N:23]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.N1CCCCC1>C(O)C>[C:16]1([C:22]2[CH2:26][CH:25]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[N:24]([C:33]3[CH:34]=[CH:35][C:36]([CH:37]=[CH:15][C:6]4[O:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:9][C:8](=[C:10]([C:11]#[N:12])[C:13]#[N:14])[CH:7]=4)=[CH:39][CH:40]=3)[N:23]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

Conditions

Temperature: 75 °C

Procedure

As shown in the following reaction 9, 0.5 g (2.5 mmol) of 2-(2-isopropyl-6-methyl-pyran-4-ylidene)-malononitrile and 0.815 g (2.5 mmol) of 4-(3,5-diphenyl-4,5-dihydro-pyrazol-1-yl)-benzaldehyde were added into 20 ml of ethanol, and 0.32 g (3.75 mmol) of piperidine was added thereto. The reaction solution was heated at 75° C. for 10 hours.

Workup

additionwas added

Sources & evidence

ORD record: ord-384fba05dab5467992f6cf3c3f64830d
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07211335B2

Reaction notes

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