Tetrahydrofuran → 2-n-Butyl-1,2,3,4-tetrahydropyrrolo[3,4-b]indole

HRID 134933Notes

Reaction equation

[Al+3:19].[CH2:1]([CH2:2][CH2:3][CH3:4])[N:5]1[C:6](=[O:17])[c:7]2[nH:8][c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[c:15]2[CH2:16]1.[H-:18].[H-:21].[H-:22].[H-:23].[Li+:20].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[N:5]1[CH2:6][c:7]2[nH:8][c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[c:15]2[CH2:16]1

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 213202522-butyl-1,4-dihydropyrrolo[3,4-b]indol-3(2H)-one

Product 1

HCID 213202552-n-Butyl-1,2,3,4-tetrahydropyrrolo[3,4-b]indole

Sources & evidence

ORD record: ord-e905da57d5824c35be5325fcc1056dc0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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