HCID 22480042, compound → HCID 22480251, compound

HRID 1349604Notes

Reaction equation

HRID 1349604 reaction equation
O1CCCCC1[N:7]1[C:15]2[C:10](=[CH:11][C:12]([NH:16][C:17]([C:19]3[CH:28]=[CH:27][C:22]([C:23]([O:25][CH3:26])=[O:24])=[CH:21][CH:20]=3)=[O:18])=[CH:13][CH:14]=2)[C:9]([C:29]2[CH:34]=[CH:33][N:32]=[CH:31][CH:30]=2)=[N:8]1>O1CCCC1.Cl>[N:32]1[CH:31]=[CH:30][C:29]([C:9]2[C:10]3[C:15](=[CH:14][CH:13]=[C:12]([NH:16][C:17]([C:19]4[CH:20]=[CH:21][C:22]([C:23]([O:25][CH3:26])=[O:24])=[CH:27][CH:28]=4)=[O:18])[CH:11]=3)[NH:7][N:8]=2)=[CH:34][CH:33]=1

Participants

4

Reactant 1

HCID 22480042HCID 22480042, compound

Product 1

HCID 22480251HCID 22480251, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared using methyl 4-[N-(1-perhydro-2H-pyran-2-yl-3-(4-pyridyl)-1H-indazol-5-yl)carbamoyl]benzoate (0.158 g, 035 mmol) as a solution in tetrahydrofuran (3 mL) and 6.0 N aqueous HCl (5 mL). The intermediate was isolated and used without further purification (0.129 g, quantitative): ES-MS (m/z) 373 [M+1]+.

Workup

  1. customThe intermediate was isolated
  2. customused without further purification (0.129 g, quantitative)

Sources & evidence

ORD record
ord-4f431e56ff2747e8bfb1449083bea532
Source dataset
uspto-grants-2007_05
Patent number
US07211594B2

Reaction notes

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