反应详情

7.5 g of the compound obtained in Step 3 and 9.57 ml of hydrazine monohydrate were added to 50 ml of n-propanol, the resulting mixture was refluxed for 6 hours, and distilled under a reduced pressure to remove the solvent. The resulting residue was dissolved in 80 ml of chloromethane, washed with water, and dried over anhydrous magnesium sulfate. The dried organic layer was concentrated under a reduced pressure to obtain 7.26 g of the title compound.

1. temperaturethe resulting mixture was refluxed for 6 hours
2. distillationdistilled under a reduced pressure
3. customto remove the solvent
4. dissolutionThe resulting residue was dissolved in 80 ml of chloromethane
5. washwashed with water
6. dry with materialdried over anhydrous magnesium sulfate
7. concentrationThe dried organic layer was concentrated under a reduced pressure