Triphenylphosphine → HCID 69519174, compound

HRID 1354231Notes

Reaction equation

HRID 1354231 reaction equation
C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[N:20]([CH2:23][C:24]1[CH2:29][N:28]([NH:30][C:31]([O:33][C:34]([CH3:37])([CH3:36])[CH3:35])=[O:32])[CH2:27][CH2:26][CH:25]=1)=[N+]=[N-]>C1COCC1.O>[NH2:20][CH2:23][C:24]1[CH2:29][N:28]([NH:30][C:31]([O:33][C:34]([CH3:37])([CH3:36])[CH3:35])=[O:32])[CH2:27][CH2:26][CH:25]=1

Participants

5

Reactant 2

HCID 11776TriphenylphosphineHCID 86603235HCID 86603235, compound

Product 1

HCID 69519174HCID 69519174, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

Triphenylphosphine on polystyrene (5.24 g) was added to a solution of tert-butyl 5-azidomethyl-3,6-dihydro-2H-pyridine-1-carbamate (1 g, 4.2 mmol) in THF (25 ml) and water (0.250 ml). The reaction mixture was shaken at room temperature for 36 hours. The polymer was filtered off and then washed with THF. The filtrate was concentrated.

Workup

  1. filtrationThe polymer was filtered off
  2. washwashed with THF
  3. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-915055fef30541c99e0f6165803acee0
Source dataset
uspto-grants-2007_05
Patent number
US07223776B2

Reaction notes

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