Hydrochloric Acid → HCID 69520324, compound

HRID 1354393Notes

Reaction equation

HRID 1354393 reaction equation
[C:1]([C:3]1[C:4]([S:10][C@@H:11]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH2:12][NH:13]C(=O)OC(C)(C)C)=[N:5][C:6]([CH3:9])=[CH:7][CH:8]=1)#[N:2].[ClH:27]>O1CCOCC1>[ClH:27].[NH2:13][CH2:12][C@@H:11]([S:10][C:4]1[C:3]([C:1]#[N:2])=[CH:8][CH:7]=[C:6]([CH3:9])[N:5]=1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86598975HCID 86598975, compound

Product 1

HCID 69520324HCID 69520324, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The product from step (c) (45 mg) was dissolved in 4M HCl in dioxane (5 ml). The resulting solution was stirred at room temperature for 15 minutes, then the solvent was evaporated off. The residue was recrystallised from diethyl ether/ethanol to give the title compound as a white solid (19 mg).

Workup

  1. customthe solvent was evaporated off
  2. customThe residue was recrystallised from diethyl ether/ethanol

Sources & evidence

ORD record
ord-101fdc1c64be4175a6927b9a5eabfeda
Source dataset
uspto-grants-2007_05
Patent number
US07223794B2

Reaction notes

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