2-Bromoethyl methyl ether → HCID 18507463, compound

HRID 1355718Notes

Reaction equation

HRID 1355718 reaction equation
[NH2:1][C:2]1[NH:3][C:4](=[S:16])[C:5]([C:14]#[N:15])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1.[CH3:17][O:18][CH2:19][CH2:20]Br.CC[O-].[Na+]>C(O)C>[NH2:1][C:2]1[N:3]=[C:4]([S:16][CH2:20][CH2:19][O:18][CH3:17])[C:5]([C:14]#[N:15])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:7]=1

Participants

5

Reactant 3

HCID 809722-Bromoethyl methyl etherHCID 2723922Sodium ethoxideHCID 178509378HCID 178509378, compound

Product 1

HCID 18507463HCID 18507463, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, 2-methoxyethyl bromide and sodium ethylate in ethanol. EI-MS m/e (%): 286 (M+, 6), 228 ([M—MeOCH═CH2]+, 100).

Sources & evidence

ORD record
ord-af5dd5073f7b4594b65c67c08c22081d
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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