Isopropanol → HCID 12862276, compound

HRID 1355781Notes

Reaction equation

HRID 1355781 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](Cl)[C:5]([C:9]#[N:10])=[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:3]=1.[CH:17]([OH:20])([CH3:19])[CH3:18].C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([O:20][CH:17]([CH3:19])[CH3:18])[C:5]([C:9]#[N:10])=[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:3]=1

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507370HCID 18507370, compound

Product 1

HCID 12862276HCID 12862276, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-chloro-6-phenyl-pyrimidine-5-carbonitrile, isopropanol and DBU in DME. EI-MS m/e (%): 254 (M+, 41), 212 ([M—C3H6]+, 55), 184 (35), 170 (100).

Sources & evidence

ORD record
ord-89a8562ed4104010bcce18fee84ab00e
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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