2-Acetylfuran → HCID 18507226, compound

HRID 1355819Notes

Reaction equation

HRID 1355819 reaction equation
[C:1]([C:4]1O[CH:6]=[CH:7][CH:8]=1)(=O)[CH3:2].COC(OC)N(C)C.[C:17](=[O:20])(O)O.[NH2:21][C:22]([NH2:24])=[NH:23].C[O-].[Na+].[I:28]N1C(=O)CCC1=O>CN(C=O)C.CO.C(O)(=O)C>[O:20]1[CH:17]=[CH:6][CH:7]=[C:8]1[C:4]1[C:1]([I:28])=[CH:2][N:21]=[C:22]([NH2:24])[N:23]=1

Participants

9

Reactant 5

HCID 145052-AcetylfuranHCID 78373Dimethylformamide dimethyl acetalHCID 120273N-IodosuccinimideHCID 286947Carbonic acid-guanidine (1:1)HCID 10942334Sodium Methoxide

Product 1

HCID 18507226HCID 18507226, compound

Reagents, catalysts & solvents 3

HCID 176Acetic AcidSolventHCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

From 2-acetylfuran and N,N-dimethylformamide dimethyl acetal in DMF. Then treatment with guanidine carbonate and sodium methylate in methanol. Then treatment with N-iodosuccinimide in acetic acid. EI-MS m/e (%): 287 (M+, 100).

Sources & evidence

ORD record
ord-614e059121314561acdbbc9cbd621f1b
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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