Isopropanol → HCID 18507670, compound

HRID 1355901Notes

Reaction equation

HRID 1355901 reaction equation
[Br:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1S(C)=O.[CH:17]([OH:20])(C)[CH3:18].C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Br:1][C:2]1[C:7]([O:20][CH2:17][CH3:18])=[N:6][C:5]([NH2:11])=[N:4][C:3]=1[C:12]1[O:13][CH:14]=[CH:15][CH:16]=1

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185072865-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine

Product 1

HCID 18507670HCID 18507670, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, isopropanol and DBU in dioxane. EI-MS m/e (%): 299 (M{81Br}+, 43), 297 (M{79Br}+, 45), 257 ([M—C6H10]+, 98), 255 ([M—C6H10]+, 100), 206 (32), 94 (44), 43 (52).

Sources & evidence

ORD record
ord-4a2cc9789503423e8c35d555f2f51f1f
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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