Butanethiol → HCID 18507381, compound

HRID 1355914Notes

Reaction equation

HRID 1355914 reaction equation
[Br:1][C:2]1[C:3]([C:12]2[O:13][CH:14]=[CH:15][CH:16]=2)=[N:4][C:5]([NH2:11])=[N:6][C:7]=1[S:8]([CH3:10])=O.[CH2:17](S)[CH2:18][CH2:19]C.C1CCN2C(=NCCC2)CC1>O1CCOCC1>[Br:1][C:2]1[C:7]([S:8][CH2:10][CH2:17][CH2:18][CH3:19])=[N:6][C:5]([NH2:11])=[N:4][C:3]=1[C:12]1[O:13][CH:14]=[CH:15][CH:16]=1

Participants

5

Reactant 3

HCID 8012ButanethiolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 185072865-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine

Product 1

HCID 18507381HCID 18507381, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, butanethiol and DBU in dioxane. EI-MS m/e (%): 329 (M{81Br}+, 29), 327 (M{79Br}+, 28), 287 ([M{81Br}-C3H6]+, 46), 285 ([M{79Br}—C3H6]+, 45), ), 273 ([M{81Br}—C4H8]+, 98), 271 ([M{79Br}—C4H8]+, 99), 248 ([M—Br]+, 54), 206 (100), 192 (34), 117 (34).

Sources & evidence

ORD record
ord-7319994e01384a47b41057df33dc65cc
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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