Benzyl Alcohol → HCID 18507706, compound

HRID 1355930Notes

Reaction equation

HRID 1355930 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10](S(C)=O)[N:9]=[C:8]([NH2:16])[N:7]=1.[CH2:17]([OH:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C1CCN2C(=NCCC2)CC1>C1COCC1>[CH2:17]([O:24][C:10]1[C:11]([I:12])=[C:6]([C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)[N:7]=[C:8]([NH2:16])[N:9]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

5

Reactant 3

HCID 244Benzyl AlcoholHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507211HCID 18507211, compound

Product 1

HCID 18507706HCID 18507706, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

From 4-furan-2-yl-5-iodo-6-methanesulfinyl-pyrimidin-2-yl-amine, benzyl alcohol and DBU in THF. ES-MS m/e (%): 394 (M+H+, 100).

Sources & evidence

ORD record
ord-149bbc849a044ac18c54ad4500310231
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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