Benzenepropanol → HCID 10112892, compound

HRID 1355937Notes

Reaction equation

HRID 1355937 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10](S(C)=O)[N:9]=[C:8]([NH2:16])[N:7]=1.[C:17]1([CH2:23][CH2:24][CH2:25][OH:26])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.C1CCN2C(=NCCC2)CC1>C1COCC1>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10]([O:26][CH2:25][CH2:24][CH2:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:9]=[C:8]([NH2:16])[N:7]=1

Participants

5

Reactant 3

HCID 31234BenzenepropanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507211HCID 18507211, compound

Product 1

HCID 10112892HCID 10112892, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

From 4-furan-2-yl-5-iodo-6-methanesulfinyl-pyrimidin-2-yl-amine, 3-phenylpropanol and DBU in THF. ES-MS m/e (%): 422 (M+H+, 100).

Sources & evidence

ORD record
ord-472ddcc51f3a4e90846668a97b03ccf7
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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