1-Butanol → HCID 18507457, compound

HRID 1355947Notes

Reaction equation

HRID 1355947 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([O:8]S(C(F)(F)F)(=O)=O)[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([C:19]2[O:20][CH:21]=[CH:22][CH:23]=2)[N:3]=1.[CH2:24](O)[CH2:25][CH2:26][CH3:27].C1CCN2C(=NCCC2)CC1>COCCOC>[CH2:24]([O:8][C:6]1[C:5]([N+:16]([O-:18])=[O:17])=[C:4]([C:19]2[O:20][CH:21]=[CH:22][CH:23]=2)[N:3]=[C:2]([NH2:1])[N:7]=1)[CH2:25][CH2:26][CH3:27]

Participants

5

Reactant 3

HCID 2631-ButanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 86583748Trifluoromethanesulfonic acid 2-amino-6-furan-2-yl-5-nitro-pyrimidin-4-yl ester

Product 1

HCID 18507457HCID 18507457, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From trifluoro-methanesulfonic acid 2-amino-6-furan-2-yl-5-nitro-pyrimidin-4-yl ester, butanol and DBU in DME. EI-MS m/e (%): 278 (M+, 24), 249 ([M—C2H5]+, 28), 193 (70), 177 (100), 150 (48), 108 (86), 94 (62), 70 (48), 69 (46), 43 (68), 41 (62), 29 (45).

Sources & evidence

ORD record
ord-f1b4e60066034d5c8c226a238eda1cbd
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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