Chlorosuccinimide → HCID 18507266, compound

HRID 1356187Notes

Reaction equation

HRID 1356187 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([O:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=2)[N:3]=1.[Cl:24]N1C(=O)CCC1=O>CN(C=O)C>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][C:10]([Cl:24])=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([O:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=2)[N:3]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 9901170HCID 9901170, compound

Product 1

HCID 18507266HCID 18507266, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

From 2-amino-4-furan-2-yl-6-(2-pyridin-2-yl-ethoxy)-pyrimidine-5-carbonitrile and N-chlorosuccinimide in DMF. ES-MS m/e (%): 344 (M{37C }+H+, 30), 342 (M{35Cl}+H+, 100).

Sources & evidence

ORD record
ord-0c531db5adf249e38c6cce2837c9d29e
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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