1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 18507291, compound

HRID 1356197Notes

Reaction equation

HRID 1356197 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[C:11]([C:13]#[N:14])[CH:12]=2)[C:5]([C:15]#[N:16])=[C:4]([S:17]([CH3:19])=O)[N:3]=1.SC[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[C:11]([C:13]#[N:14])[CH:12]=2)[C:5]([C:15]#[N:16])=[C:4]([S:17][CH2:19][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=2)[N:3]=1

Participants

5

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 1509632-PyridineethanethiolHCID 18507394HCID 18507394, compound

Product 1

HCID 18507291HCID 18507291, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-(4-cyano-furan-2-yl)-6-methanesulfinyl-pyrimidine-5-carbonitrile, 2-mercaptoethylpyridine and DBU in DME. EI-MS m/e (%): 348 (M+, 90), 347 ([M—H]+, 65), 138 (100), 106 (70).

Sources & evidence

ORD record
ord-b7ecd6de610a4dc2af621cf541f1edbc
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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