Triethylamine → HCID 18507528, compound

HRID 1356198Notes

Reaction equation

HRID 1356198 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:8](=[C:11]([S:14][CH3:15])SC)[C:9]#[N:10])=O.[CH3:16][O:17][CH2:18][CH2:19][N:20]([CH2:22][C:23]1[CH:34]=[CH:33][C:26]([C:27]([NH:29][C:30]([NH2:32])=[NH:31])=[O:28])=[CH:25][CH:24]=1)[CH3:21].C(N(CC)CC)C>CN(C=O)C>[C:9]([C:8]1[C:6]([C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)=[N:31][C:30]([NH:29][C:27](=[O:28])[C:26]2[CH:25]=[CH:24][C:23]([CH2:22][N:20]([CH2:19][CH2:18][O:17][CH3:16])[CH3:21])=[CH:34][CH:33]=2)=[N:32][C:11]=1[S:14][CH3:15])#[N:10]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 28190932-(furan-2-carbonyl)-3,3-bis-methylsulfanyl-acrylonitrileHCID 178495914HCID 178495914, compound

Product 1

HCID 18507528HCID 18507528, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

From 2-(furan-2-carbonyl)-3,3-bis-methylsulfanyl-acrylonitrile, N-(4-{[(2-methoxy-ethyl)-methyl-amino]-methyl}-benzoyl)-guanidine and triethylamine in DMF. ES-MS m/e (%): 438 (M+H+, 100).

Sources & evidence

ORD record
ord-7c14f45f55a948b2a0a74c80d19e8835
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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