Water → HCID 18509283, compound

HRID 1356622Notes

Reaction equation

HRID 1356622 reaction equation
[CH3:1][O:2][C:3]1[CH:19]=[CH:18][C:6]([NH:7][S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)(=[O:10])=[O:9])=[C:5]([N+:20]([O-:22])=[O:21])[CH:4]=1.[C:23]1([CH3:33])[CH:28]=[CH:27][C:26]([S:29](Cl)(=[O:31])=[O:30])=[CH:25][CH:24]=1.O>N1C=CC=CC=1>[C:14]1([CH3:17])[CH:13]=[CH:12][C:11]([S:8]([N:7]([S:29]([C:26]2[CH:27]=[CH:28][C:23]([CH3:33])=[CH:24][CH:25]=2)(=[O:31])=[O:30])[C:6]2[CH:18]=[CH:19][C:3]([O:2][CH3:1])=[CH:4][C:5]=2[N+:20]([O-:22])=[O:21])(=[O:10])=[O:9])=[CH:16][CH:15]=1

Participants

5

Reactant 3

HCID 962WaterHCID 73974-Toluenesulfonyl chlorideHCID 225676N-(4-Methoxy-2-nitrophenyl)-4-methylbenzenesulfonamide

Product 1

HCID 18509283HCID 18509283, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 4′-Methoxy-2′-nitro-p-toluenesulfonanilide (0.32 g (1.00 mmol)) in pyridine (1,0 ml), p-toluenesulfonyl chloride (0.20 g (1.05 mmol)) was added with stirring at room temperature. After 15 hours' stirring at room temperature, the reaction mixture was poured into water and crystals separated was filtered and washed to give 0.34 g (83%) of the title compound as pale yellow crystals.

Workup

  1. stirringAfter 15 hours' stirring at room temperature
  2. customseparated
  3. filtrationwas filtered
  4. washwashed

Sources & evidence

ORD record
ord-3f1dbecdb1784d3980671684b12d3491
Source dataset
uspto-grants-2003_07
Patent number
US06586617B1

Reaction notes

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