1-Amino-2-propanol → HCID 18003353, compound

HRID 1358167Notes

Reaction equation

HRID 1358167 reaction equation
[NH2:1][CH2:2][CH:3]([OH:5])[CH3:4].[N+:6]([CH:9]([CH3:11])[CH3:10])([O-:8])=[O:7].[CH2:12]=O>C(O)(C)C>[N+:6]([C:9]([CH3:12])([CH3:11])[CH2:10][NH:1][CH2:2][CH:3]([OH:5])[CH3:4])([O-:8])=[O:7]

Participants

5

Reactant 3

HCID 41-Amino-2-propanolHCID 3982-NitropropaneHCID 712Formaldehyde

Product 1

HCID 18003353HCID 18003353, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Following the procedure described below in EXAMPLE 4A, step 1, 526.3 g (6.66 mol) of 1-amino-2-propanol (95%) are reacted with 561.6 g (6.05 mol) of 2-nitropropane (96%) and 181.7 g (6.05 mol) of paraformaldehyde in 100 ml of isopropanol to give the product which is used in the following reaction without any isolation.

Workup

  1. customto give the product which
  2. customis used in the following reaction without any isolation

Sources & evidence

ORD record
ord-ac1a6740bf274675af3e11941d0116c5
Source dataset
uspto-grants-2003_07
Patent number
US06596461B1

Reaction notes

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