Oxalyl chloride → 2-(3,4-Dichlorophenyl)acetyl chloride

HRID 1358469Notes

Reaction equation

HRID 1358469 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=O)[CH:5]=[CH:6][C:7]=1[Cl:8].C(Cl)(=O)C([Cl:16])=O>C1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([Cl:16])=[O:12])[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 798743,4-Dichlorophenylacetic acid

Product 1

HCID 27581492-(3,4-Dichlorophenyl)acetyl chlorideYield 100%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of (3,4-dichloro-phenyl) acetic acid (3.51 g, 0.0179 mol) and oxalyl chloride (17.5 g, 12.08 mL, 0.089 mol) in 150 mL of benzene was refluxed for 6 h. The solution was evaporated with benzene 3 times and dried in vacuum. Yield 100%.

Workup

  1. customThe solution was evaporated with benzene 3 times
  2. customdried in vacuum

Sources & evidence

ORD record
ord-c5bf20ff8c2c490ca43a4fe15379f5eb
Source dataset
uspto-grants-2003_07
Patent number
US06596734B1

Reaction notes

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