4-Hydroxybenzaldehyde → 4-Hydroxybenzyl Alcohol

HRID 1359618Notes

Reaction equation

HRID 1359618 reaction equation
[H][H].[OH:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[O:9])=[CH:6][CH:5]=1.C(=O)C1C=CC=CC=1>CO>[OH:3][C:4]1[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 1264-HydroxybenzaldehydeHCID 240BenzaldehydeHCID 178418361HCID 178418361, compound

Product 1

HCID 1254-Hydroxybenzyl Alcohol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A 1.0 g quantity of the catalyst (CuO/ZnO/Aluminium oxide) in 50 ml methanol was placed in a 300 ml capacity Parr reactor. The contents were treated with hydrogen at 170° C., under pressure of 400-500 psig for 2-3 hrs. Cooled to room temperature, depressurized, followed by the addition of 10.0 g of 4-hydroxybenzaldehyde, in 50 ml of methanol. Hydrogenation was carried out at 170° C., under a pressure of 400-500 psig, for 2-3 hrs. The conversion of benzaldehyde was 100% providing 100% selectivity of 4-hydroxybenzyl alcohol, the desired alcohol product.

Sources & evidence

ORD record
ord-4eee963bc48449b79654b109c4eb08fd
Source dataset
uspto-grants-2003_07
Patent number
US06600078B1

Reaction notes

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