Tetrahydrofuran → 4,6-dichloro-N-[1-(4-fluorophenyl)ethyl]pyrimidin-2-amine
Reaction equation
[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[Cl:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1.[F:17][c:18]1[cH:19][cH:20][c:21]([CH:24]([CH3:25])[NH2:26])[cH:22][cH:23]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[c:2]1([NH:26][CH:24]([c:21]2[cH:20][cH:19][c:18]([F:17])[cH:23][cH:22]2)[CH3:25])[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-61b1b831f4654365b5047b0e9938582c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…