反应详情

温度

50 °C

144 g (0.576 mol) of 2-chloro-4-methyl-1,3-thiazole-5-sulfonamide are introduced at room temperature into 600 ml of acetonitrile, and 147 g (1.9 mol) of 40% strength aqueous methylamine solution are metered in at room temperature. The reaction mixture is stirred at 50° C. for 6 h and then concentrated in a rotary evaporator. The residue is mixed with water, filtered with suction and dried.

1. customare metered in at room temperature
2. concentrationconcentrated in a rotary evaporator
3. additionThe residue is mixed with water
4. filtrationfiltered with suction
5. customdried