HRID1363008

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

结构：CCCCc1cc(O[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c2ncccc2c1

HCID66921936

未命名化合物

2 次

PRODUCTS

生成物

HCID66921730

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

This was prepared in an analogous manner to Intermediate 4, using 1,1-dimethylethyl (3R)-3-[(6-butyl-8-quinolinyl)oxy]-1-pyrrolidinecarboxylate (for example, as prepared for Intermediate 9) and 4 M hydrogen chloride in 1,4-dioxane instead of trifluoroacetic acid for 45 min. LCMS RT=2.46 min, ES+ve m/z 271 (M+H)+.

WORKUP

后处理

customfor 45 min