反应详情

2-Bromo-4-nitrobenzoic acid (3 g, 12.2 mmol) was reacted with sodium methoxide (6 g, 111 mmol) in dry DMSO (250 mL) at 80° C. After completion of reaction mixture was poured over crushed ice, acidified with 1:1 HCl and extracted with EtOAc (3×150 mL). The organic layer was concentrated to obtain the title compound.

1. customAfter completion of reaction mixture
2. additionwas poured
3. customover crushed ice
4. extractionextracted with EtOAc (3×150 mL)
5. concentrationThe organic layer was concentrated