Diethyl Ether → 1-Octyl-4-(prop-2-YN-1-YL)benzene

HRID 136616Notes

Reaction equation

HRID 136616 reaction equation
[C:18]([Br:19])([Br:20])([Br:21])[Br:22].[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[c:9]1[cH:10][cH:11][c:12]([CH2:15][CH:16]=[O:17])[cH:13][cH:14]1.[CH2:42]([Li:43])[CH2:44][CH2:45][CH3:46].[CH2:47]([Cl:48])[Cl:49].[CH2:50]([O:51][CH2:52][CH3:53])[CH3:54].[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1.[Zn:60].[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[c:9]1[cH:10][cH:11][c:12]([CH2:15][C:16]#[CH:18])[cH:13][cH:14]1

Participants

9

Reactant 8

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 23994ZincHCID 53716894(4-Octylphenyl)acetaldehydeHCID 178418339Butyllithium

Product 1

HCID 204880011-Octyl-4-(prop-2-YN-1-YL)benzene

Sources & evidence

ORD record
ord-e250234a65054bafbef586243225ec95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…