反应详情

A solution of 2-methoxy-N-(6-methylpyridin-3-yl)methyl-4-nitrobenzamide (448 mg, 1.49 mmol) in EtOH and EtOAc (8 mL each) is stirred and ammonium formate (375 mg, 6 mmol) and 10% Pd/C (100 mg) are added. The mixture is heated at reflux for 20 min, cooled, filtered through celite, the solid is washed with EtOH and the combined solvents are evaporated to afford the title compound.

1. temperatureThe mixture is heated
2. temperatureat reflux for 20 min
3. temperaturecooled
4. filtrationfiltered through celite
5. washthe solid is washed with EtOH
6. customthe combined solvents are evaporated