反应详情

To a solution of 1,1-dimethylethyl [(3S)-1-methyl-2-oxohexahydro-1H-azepin-3-yl]carbamate (470 mg, 1.9 mmol) in dioxane (5 mL) was added HCl (4.8 mL, 19 mmol, 4M in dioxane), and the reaction was stirred overnight. Evaporation of the solvent gave a quantitative yield of (3S)-3-amino-1-methylhexahydro-2H-azepin-2-one. LCMS: (M+H)+: 143.1.

1. customEvaporation of the solvent