Dimethylformamide → trans-3-{4-[(6-Chloro-pyridazin-3-yl)-methyl-amino]-cyclohexyl}-prop-2-yn-1-ol
Reaction equation
[CH2:21]([N:22]([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28])[CH3:29].[CH3:1][NH:2][CH:3]1[CH2:4][CH2:5][CH:6]([C:9]#[C:10][CH2:11][OH:12])[CH2:7][CH2:8]1.[Cl:13][c:14]1[n:15][n:16][c:17]([Cl:20])[cH:18][cH:19]1.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[CH3:1][N:2]([CH:3]1[CH2:4][CH2:5][CH:6]([C:9]#[C:10][CH2:11][OH:12])[CH2:7][CH2:8]1)[c:17]1[n:16][n:15][c:14]([Cl:13])[cH:19][cH:18]1Participants
5
Sources & evidence
- ORD record
- ord-34883c945e76463ca583f48bd7507495
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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