反应详情

Analogously to Example 10A, 9.75 g (42.3 mmol) of 2-(3,4-dimethoxyphenyl)ethanamidine hydrochloride are reacted with 2.54 g (50.7 mmol) of hydrazine hydrate and 12.8 g (63.4 mmol) of ethyl 3-(acetylamino)-2-oxopentanoate to give N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}acetamide.