反应详情

Analogously to Example 40A, 0.76 g (6.00 mmol) of oxalyl chloride, 1.01 g (12.9 mmol) of dimethyl sulphoxide, 1.95 g (3.93 mmol) of 2-(1-hydroxyethyl)-N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]ethyl}-5-phenyl-pentanamide and 4.36 g (43.1 mmol) of triethylamine are reacted to give 2-acetyl-N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]ethyl}-5-phenylpentanamide.