1,2-Dichloroethane → 2-[6-(3,5-difluorophenyl)-3,3-dimethyl-2,4-dioxopiperidin-1-yl]-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)acetamide
Reaction equation
[CH2:52]([Cl:53])[CH2:54][Cl:55].[F:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][C:11](=[O:22])[C:12]([CH3:20])([CH3:21])[C:13](=[O:19])[N:14]2[CH2:15][C:16](=[O:17])[OH:18])[cH:5][c:6]([F:8])[cH:7]1.[NH2:23][c:24]1[cH:25][c:26]2[c:30]([cH:31][cH:32]1)[CH2:29][C:28]1([CH2:27]2)[C:33](=[O:41])[NH:34][c:35]2[n:36][cH:37][cH:38][cH:39][c:40]21.[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[OH:42][n:43]1[c:44]2[c:45]([cH:46][cH:47][cH:48][cH:49]2)[n:50][n:51]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][C:11](=[O:22])[C:12]([CH3:20])([CH3:21])[C:13](=[O:19])[N:14]2[CH2:15][C:16](=[O:17])[NH:23][c:24]2[cH:25][c:26]3[c:30]([cH:31][cH:32]2)[CH2:29][C:28]2([CH2:27]3)[C:33](=[O:41])[NH:34][c:35]3[n:36][cH:37][cH:38][cH:39][c:40]32)[cH:5][c:6]([F:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6d068e707b7f41b58f486dfe3db7e37e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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