Ethyl Acrylate → HCID 12375248, compound

HRID 1369020Notes

Reaction equation

HRID 1369020 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([CH3:9])[CH:3]=1.[Na].[C:11]([O:15][CH2:16][CH3:17])(=[O:14])[CH:12]=[CH2:13]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:13][CH2:12][C:11]([O:15][CH2:16][CH3:17])=[O:14])=[C:4]([CH3:9])[CH:3]=1

Participants

5

Reactant 3

HCID 8821Ethyl AcrylateHCID 148554-Chloro-2-methylphenolHCID 5360545Sodium

Product 1

HCID 12375248HCID 12375248, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The sub-title compound was prepared according to the method described in Example 27(i) above from 4-chloro-2-methylphenol (4.99 g; 35.0 mmol), sodium (0.055 g; 2.4 mmol), ethanol (1.5 mL) and ethyl acrylate (4.1 g; 41 mmol). The crude product (1.98 g; 23%) was used for the next step without further purification.

Workup

  1. customThe crude product (1.98 g; 23%) was used for the next step without further purification

Sources & evidence

ORD record
ord-c92d44a2090643c383c1e956efa76ce8
Source dataset
uspto-grants-2003_06
Patent number
US06576657B2

Reaction notes

Loading…