Hydrochloric Acid → 3-(Ethanesulfonyl)propan-1-amine hydrochloride

HRID 1371399Notes

Reaction equation

HRID 1371399 reaction equation
[CH2:1]([S:3]([CH2:6][CH2:7][CH2:8][NH:9]C(=O)OC(C)(C)C)(=[O:5])=[O:4])[CH3:2].[ClH:17]>O1CCOCC1>[ClH:17].[CH2:1]([S:3]([CH2:6][CH2:7][CH2:8][NH2:9])(=[O:5])=[O:4])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 23089203tert-Butyl 3-(ethylsulfonyl)propylcarbamate

Product 1

HCID 230892043-(Ethanesulfonyl)propan-1-amine hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Intermediate 39 (0.275 g) was dissolved in 4M hydrogen chloride in dioxane (3 ml), and the solution was allowed to stand at 22° C. for 2 h. The solvent was evaporated in vacuo to give the title compound as a white solid (186 mg).

Workup

  1. customThe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-d288090551eb491dabb37bae96dc05ac
Source dataset
uspto-grants-2007_01
Patent number
US07157457B2

Reaction notes

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