Hydrochloric Acid → (+/-)-4-[[4-(3-chlorophenyl)-1,2-dihydro-1-methyl-2-oxo-6-quinolinyl]hydroxy(1-methyl-1H-imidazol-5-yl)methyl]benzaldehyde

HRID 137203Notes

Reaction equation

HRID 137203 reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[Cl:4][c:5]1[cH:6][c:7](-[c:11]2[cH:12][c:13](=[O:37])[nH:14][c:15]3[cH:16][cH:17][c:18]([C:21]([c:22]4[cH:23][cH:24][c:25]([CH:26]=[O:27])[cH:28][cH:29]4)([c:30]4[cH:31][n:32][cH:33][n:34]4[CH3:35])[OH:36])[cH:19][c:20]23)[cH:8][cH:9][cH:10]1.[ClH:3].[I:1][CH3:2].[Na+:40].[OH-:39].[OH2:38]>>[CH3:2][n:14]1[c:13](=[O:37])[cH:12][c:11](-[c:7]2[cH:6][c:5]([Cl:4])[cH:10][cH:9][cH:8]2)[c:20]2[c:15]1[cH:16][cH:17][c:18]([C:21]([c:22]1[cH:23][cH:24][c:25]([CH:26]=[O:27])[cH:28][cH:29]1)([c:30]1[cH:31][n:32][cH:33][n:34]1[CH3:35])[OH:36])[cH:19]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 99563344-[[4-(3-chlorophenyl)-2-oxo-1H-quinolin-6-yl]-hydroxy-(3-methylimidazol-4-yl)methyl]benzaldehyde

Product 1

HCID 10299684(+/-)-4-[[4-(3-chlorophenyl)-1,2-dihydro-1-methyl-2-oxo-6-quinolinyl]hydroxy(1-methyl-1H-imidazol-5-yl)methyl]benzaldehyde

Sources & evidence

ORD record
ord-74ea21726dc447e5ab1e9ed40fa1f9c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…