反应详情

A solution of 3-methylsulfonylbenzoic acid (16.3 g) in 20% oleum (100 ml) was cooled (ice-bath) and fuming nitric acid (>90%; 90 ml) was added dropwise. The resulting mixture was stirred for 4 days at room temperature and was then poured onto crushed ice. The acids were partially neutralised by addition of solid sodium bicarbonate (to ˜pH2). The solid precipitate was filtered off and dried to give, as a pale beige solid D11 (15.6 g).

1. additionwas added dropwise
2. additionwas then poured
3. customonto crushed ice
4. filtrationThe solid precipitate was filtered off
5. customdried
6. customto give, as a pale beige solid D11 (15.6 g)