Pentanal → Cyclopentanone, 2-(1-hydroxypentyl)-

HRID 1373491노트

반응식

HRID 1373491 반응식
[CH:1](=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].[OH-].[K+].[C:9]1(=[O:14])[CH2:13][CH2:12][CH2:11][CH2:10]1>[OH-].[Na+].C(=C1CCCC1=O)CCCC.O>[OH:6][CH:1]([CH:10]1[CH2:11][CH2:12][CH2:13][C:9]1=[O:14])[CH2:2][CH2:3][CH2:4][CH3:5]

참가 물질

7

반응물 3

HCID 8063Pentanal2회HCID 8452CyclopentanoneHCID 14797Potassium Hydroxide

생성물 1

HCID 162060Cyclopentanone, 2-(1-hydroxypentyl)-수율 90.5%

시약·촉매·용매 3

HCID 14798Sodium Hydroxide촉매HCID 860002-Pentylidenecyclopentanone촉매HCID 962Water용매

반응 조건

온도
15 °C

실험 절차

Valeraldehyde having an acid value of 2.1 mg-KOH/g was used as the starting material. 199 g (2.37 mol) of cyclopentanone, 60 g of water and 1.2 g (0.014 mol) of 48% NaOH were introduced into a 500-mL four-necked flask. Then the mixture was cooled to 15° C. under stirring and 60 g (0.70 mol) of valeraldehyde was added dropwise at the same temperature over 5 hours. Thereafter, the mixture was stirred at the same temperature for 2 hours. After the reaction had finished, the mixture was neutralized and analyzed in the same manner as in Example 1. The result indicated that the reaction mixture contained 107 g (0.63 mol) of 2-(1-hydroxy-n-pentyl)cyclopentanone (yield 90.5%) and 2.0 g (0.013 mol) 2-pentylidene cyclopentanone.

후처리

  1. stirringThereafter, the mixture was stirred at the same temperature for 2 hours

출처 및 근거

ORD 기록
ord-da5b614aac10462685540790ebbaab78
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07161041B2

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