huagongshe.com
HRID1373716

反应详情

EQUATION

反应方程式

HRID 1373716 的结构方程式

REACTANTS

反应物

3
结构：C=O
HCID712

Formaldehyde

CH2O

结构：[BH3-]C#N.[Na+]
HCID5003444

Sodium cyanotrihydroborate

CH3BNNa

结构：O=C(Nc1ccc(Cl)cn1)c1cc(Cl)ccc1NC(=O)C1CCN(C2CCCNCC2)CC1
HCID21075319

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCCC(N2CCC(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)CC2)CC1
HCID21075317

未命名化合物

PROCEDURE

实验过程

Alternatively, 5-chloro-2-[1-(1-methyl-hexahydroazepin-4-yl)piperidin-4-ylcarbonylamino]-N-(5-chloropyridin-2-yl)-benzamide is prepared by a NaCNBH3 reductive alkylation of 5-chloro-2-[1-(hexahydroazepin-4-yl)piperidin-4-ylcarbonylamino]-N-(5-chloropyridin-2-yl)benzamide with formaldehyde.