Methylamine → HCID 21077597, compound

HRID 1374643Notes

Reaction equation

HRID 1374643 reaction equation
[CH3:1][S:2][C:3]1[N:8]=[C:7](Cl)[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][N:4]=1.[CH3:16][NH2:17].C(Cl)Cl.CO>C(O)C>[CH3:1][S:2][C:3]1[N:8]=[C:7]([NH:17][CH3:16])[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 6329MethylamineHCID 110209004-Chloro-2-(methylthio)-5-phenylpyrimidineHCID 21226129Dichloromethane methanol

Product 1

HCID 21077597HCID 21077597, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared from 2-methylsulphenyl-4-chloro-5-phenyl-pyrimidine by reacting with methylamine in ethanol at 90° C., Rf value: 0.63 (silica gel; methylene chloride/methanol=20:1)

Sources & evidence

ORD record
ord-431fdcfd98004bca8946444124ab1364
Source dataset
uspto-grants-2007_01
Patent number
US07166599B2

Reaction notes

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