Methylamine → HCID 21077591, compound

HRID 1374644Notes

Reaction equation

HRID 1374644 reaction equation
[CH3:1][S:2][C:3]1[N:8]=[C:7](Cl)[C:6]([Cl:10])=[CH:5][N:4]=1.[CH3:11][NH2:12].C1CCCCC1.C(OCC)(=O)C>C(O)C>[CH3:1][S:2][C:3]1[N:8]=[C:7]([NH:12][CH3:11])[C:6]([Cl:10])=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 6329MethylamineHCID 142708504,5-Dichloro-2-(methylsulfanyl)pyrimidineHCID 21867204Cyclohexane ethylacetate

Product 1

HCID 21077591HCID 21077591, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared from 2-methylsulphenyl-4,5-dichloro-pyrimidine by reacting with methylamine in ethanol at 90° C., melting point: 241° C., Rf value: 0.59 (silica gel; cyclohexane/ethyl acetate=2:1)

Sources & evidence

ORD record
ord-221370aad7494892ae7fc36e4c63fac3
Source dataset
uspto-grants-2007_01
Patent number
US07166599B2

Reaction notes

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