m-Chloroperbenzoic acid → 2-Methylsulphinyl-4-methylamino-5-methyl-pyrimidine

HRID 1374648Notes

Reaction equation

HRID 1374648 reaction equation
[CH3:1][S:2][C:3]1[N:8]=[C:7]([NH:9][CH3:10])[C:6]([CH3:11])=[CH:5][N:4]=1.ClC1C=C(C=CC=1)C(OO)=[O:17].C(Cl)Cl.CO>C(Cl)Cl>[CH3:1][S:2]([C:3]1[N:8]=[C:7]([NH:9][CH3:10])[C:6]([CH3:11])=[CH:5][N:4]=1)=[O:17]

Participants

5

Reactant 3

HCID 70297m-Chloroperbenzoic acidHCID 241191HCID 241191, compoundHCID 21226129Dichloromethane methanol

Product 1

HCID 210776012-Methylsulphinyl-4-methylamino-5-methyl-pyrimidine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from 2-methylsulphenyl-4-methylamino-5-methyl-pyrimidine by reacting with 3-chloro-peroxybenzoic acid in methylene chloride, Rf value: 0.23 (silica gel; methylene chloride/methanol/ conc. aqueous ammonia=20:1:0.1)

Sources & evidence

ORD record
ord-ede1d5379e934237a600435a4149b0e6
Source dataset
uspto-grants-2007_01
Patent number
US07166599B2

Reaction notes

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