反应详情

5.4 g (20 mmol) of 4-(N-bromomethylcarbonyl-N-methyl-amino)-nitrobenzene are dissolved in 100 ml of acetone and combined with 5.5 g (40 mmol) of potassium carbonate. 3 ml (30 mmol) of piperidine are slowly added dropwise and the mixture is stirred for 18 hours at ambient temperature. The reaction solution is filtered, and the filtrate is evaporated to dryness. The residue is dissolved in ethyl acetate, washed with water, dried over magnesium sulphate and evaporated to dryness.

1. filtrationThe reaction solution is filtered
2. customthe filtrate is evaporated to dryness
3. dissolutionThe residue is dissolved in ethyl acetate
4. washwashed with water
5. dry with materialdried over magnesium sulphate
6. customevaporated to dryness