反应详情

2-Methoxybenzyl alcohol (1.01 g, 7.31 mmol) and triphosgene (757 mg, 2.55 mmol) were dissolved in tetrahydrofuran (5 ml). The solution was added with pyridine (1.18 ml, 14.6 mmol) under ice cooling, and then warmed to room temperature. After 20 minutes, insoluble solids were removed by filtration, and the solvent was evaporated under reduced pressure. The resulting oil was diluted with ethyl acetate and insoluble solids were further removed. The solvent was evaporated under reduced pressure to obtain the title compound as pale yellow oil (1.16 g, yield: 100%).

1. custominsoluble solids were removed by filtration
2. customthe solvent was evaporated under reduced pressure
3. additionThe resulting oil was diluted with ethyl acetate and insoluble solids
4. customwere further removed
5. customThe solvent was evaporated under reduced pressure