反应详情

温度

100 °C

Chloroacetyl chloride (0.32 ml, 4.02 mmol) was dissolved in a mixed solvent of toluene (6 ml) and tetrahydrofuran (2 ml). The solution was added with diphenylamine (690 mg, 4.08 mmol) at room temperature, and the heated at 100° C. for 80 minutes. The solvent was evaporated under reduced pressure, and the solid precipitated was suspended and washed in ethyl ether. The solid was collected by filtration and dried under reduced pressure to obtain the title compound as colorless solid (746 mg, yield: 75%).

1. customThe solvent was evaporated under reduced pressure
2. customthe solid precipitated
3. washwashed in ethyl ether
4. filtrationThe solid was collected by filtration
5. customdried under reduced pressure