反应详情

温度

60 °C

A mixture of 382 mg (2.0 mmol) A1, 337 mg (2.2 mmol) methyl bromoacetate and 387 mg (2.8 mmol) potassium carbonate in 6 ml dry acetone were stirred for 2 h at 60° C. After filtration and removal of the solvent the residue was purified by column chromatography on SiGel (hexane/ethyl acetate 4:1). Yield: 508 mg (97%) A4, colorless solid.

1. filtrationAfter filtration and removal of the solvent the residue
2. customwas purified by column chromatography on SiGel (hexane/ethyl acetate 4:1)