Potassium Carbonate → HCID 21897138, compound

HRID 1375477Notes

Reaction equation

HRID 1375477 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1.[C:26]([O-])([O-])=[O:27].[K+].[K+]>CO>[CH3:26][O:27][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 218970216-chloro-N-(3-chloro-4-methoxyphenyl)-N'-cycloheptyl-[1,3,5]triazine-2,4-diamine

Product 1

HCID 21897138HCID 21897138, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To 6-chloro-N-(3-chloro-4-methoxyphenyl)-N′-cycloheptyl-[1,3,5]triazine-2,4-diamine (5 g) dissolved in methanol was added K2CO3 (3.2 g) and refluxed for about 6–8 h. TLC was monitored. After the completion of the reaction, the reaction mass was filtered through vacuum and the filtrate was evaporated to yield the title compound. (Wt. 4.7 g Y: 95%)

Workup

  1. temperaturerefluxed for about 6–8 h
  2. customAfter the completion of the reaction
  3. filtrationthe reaction mass was filtered through vacuum
  4. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-6dfb8cb579e74cf388326681cf9ba921
Source dataset
uspto-grants-2007_01
Patent number
US07169784B2

Reaction notes

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