Methyl Ethyl Ketone → Benzoic Acid

HRID 1377108Notes

Reaction equation

HRID 1377108 reaction equation
F[C:2]1C=C[C:5](C)=[CH:4][CH:3]=1.C[C:10]([CH2:12][CH3:13])=[O:11].[O:14]=O.CCCC>C(O)(=O)C.O.O.O.O.C([O-])(=O)C.C([O-])(=O)C.[Co+2]>[C:10]([OH:11])(=[O:14])[C:12]1[CH:13]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

6

Reactant 3

HCID 6569Methyl Ethyl KetoneHCID 9603p-FluorotolueneHCID 131720182HCID 131720182, compound

Product 1

HCID 243Benzoic Acid

Reagents, catalysts & solvents 2

HCID 61372Cobalt(II) acetate tetrahydrateCatalystHCID 176Acetic AcidSolvent

Procedure

Para-Fluorotoluene derivatives B16 are heated at about 90° C. to 110° C. for about 2-3 hours with cobalt diacetate-tetrahydrate and ethyl methyl ketone in acetic acid under pressure of oxygen-butane to produce benzoic acid derivatives B1.

Sources & evidence

ORD record
ord-0e091eeb4f194b19a0d50530c648c37b
Source dataset
uspto-grants-1997_09
Patent number
US05663448

Reaction notes

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