反应详情

A solution of 1,5-bis(4-hydroxyphenyl)-3-pentanone (2.0 g, 8 mmol), prepared as in step 2, and potassium carbonate (2.76 g, 20 mmol) in DMF (40 mL) was treated with chloromethylquinoline (3.55 g, 20 mmol) at room temperature for 36 hours. The mixture was then poured into ice water (200 mL), and the precipitated solid was filtered, washed with water and dried in vacuo to afford crude 1,5-bis(4-(2-quinolylmethoxy)phenyl)-3-pentanone (5 g) which was used without further purification.

1. filtrationthe precipitated solid was filtered
2. washwashed with water
3. customdried in vacuo